English français

Scanelis

Home > Scanelis

Scanelis

  • Who we are

    The Scanelis laboratory is specialised in molecular diagnostics in the field of animal health.

    In 2000, Scanelis was the first laboratory which offered routine quantitative PCR analyses for detection, quantification and typing of pathogens in animals.

    Diagnostic laboratory

    Specialist in real-time PCR (Polymerase Chain Reaction), Scanelis offers approximately 60 real-time PCR assays, for the detection/quantification of infectious agents in many animal species (dogs, cats, birds, ferrets, exotics, cattle, sheep and goats, poultry and rabbits, horses, fishes).

    All the Scanelis PCR assays have been developed and validated by our R&D department.

    Our production department performs day-to-day analyses in a secured lab, dedicated to this technology to provide veterinarians with fast and efficient diagnoses.

    Support to Industry

    Scanelis also provides support to industry, biotechs, lab animal suppliers and research labs:

    • Health monitoring for laboratory animals
    • Real-time PCR genetic testing
    • Quality control of biopharmaceuticals by real-time PCR testing
    • Diagnostics performed in accordance with a customer’s
      specifications or prescribed quality plan, for instance with the European Pharmacopoeia recommendations.
    • Custom-designed investigations: molecular typing of isolates or strains, infection monitoring and epidemiological monitoring, pathogens or mRNA quantification, cloning and DNA quantification...

    All the publications of the Scanelis coworkers

  • The Scanelis Laboratory

    Our premises

    A 350 m² laboratory dedicated to PCR

    • 2 analytical lines: Infectious diseases / Genetics, Quality Control of biopharmaceuricals
    • Compliance with GLP and pharmaceutical standards
    • Air flow control: positive / negative pressure
    • A state-of-the-art laboratory
    Environmentally friendly with geoclimatic conception and wood construction
    Discover our lab in pictures during an interview of our President

    Technical platform

    All the equipments are in duplicate for a continuous service in case of maintenance or failure.

    • quantitative PCR (real-time PCR): 4 Thermocyclers including 2 Sequence Detection System, ABI 7900 and 2 ABI QS6
    • liquid-handling: 2 Microlab Star workstations, Hamilton
    • Laboratory Information Management System (LIMS)

  • Assay development

    Diagnostic Laboratory

    All quantitative PCR assays performed in our analytical laboratory have been developed and validated by the Scanelis Research and Development department.

    Our specifications are very strict:

    • the test must be adapted to the field needs (quantitative aspect, vaccine strain typing, pathogen strain detection).
    • the analytical specificity of the test is assessed on reference strains and field strains. Sequencing is performed to check it during the validation stages.
    • the limit of detection which assesses the sensitivity of the test is determined by statistical studies (Probit analyses) according to the European pharmacopoeia recommendations. A 95 % detection limit is thus calculated. Appropriate positive controls are then used for each analytical series to check this limit of detection for each analysis.
    • the rate of asymptomatic carriers and the level of carriage (bacterial or viral load) are also assessed on different field populations to determine the clinical usefulness of the test (diagnostic specificity), in particular as compared with other diagnosis methods.

    Support to industry

    Scanelis also develops custom-designed assays, respecting these specifications and according to customers’ needs (clinical trials, quality control for the chemist industry, etc.).
    Scanelis is able to assess the performance of a particular test developed by a customer (for limit of detection, specificity, reproducibility, etc).

  • Quality management

    Scanelis analyses are performed within a strict quality assurance program according to ISO 17025 standards.

    Monitoring and traceability of analyses
    A Laboratory Information Management System (LIMS) is being installed at the Scanelis laboratory offering fully automated monitoring of samples from their registration to delivery of the results and invoicing.

    Premises
    The Scanelis’ laboratory has been designed to offer high safety & security and to ensure a strict forward workflow of samples.

    Assay development and validation
    All assays are developed in accordance with the European Pharmacopoeia recommendations (2.6.21) and NF U47-600-2 standards.

    Analyses for quality control of biological products
    A specific quality plan is set up in accordance with the European Pharmacopoeia recommendations and can be adapted to meet customers requirements and specifications.

  • Scanelis Publications & partnerships

    Scanelis publications are listed below. When it is possible do not hesitate to download these ones.

    Scanelis Publications

    		 Distemper disease
    - Boucraut-Baralon, C., C. Trumel. 2000. Diagnostic de la maladie de Carré, le choix d’une technique. Le Nouveau Praticien Vétérinaire Août-Septembre-Octobre 2000 : 51-53
    - Boucraut-Baralon, C. . 2006. Comment diagnostiquer et prévenir la maladie de Carré chez le chien et le furet. Le Nouveau Praticien Vétérinaire canine, féline Hors-série 2006 : 83-87
    Mycobacteria
    - Etienne C.-L., F. Granat, C. Trumel, I. Raymond-Letron, M.-N. Lucas, C. Boucraut-Baralon, J.-L. Pingret, L. Magne, M. Delverdier. 2013. A mycobacterial coinfection in a dog suspected on blood smear. 2013 42/4 : 516-521
    Enteritic pathogens
    - Broussou, D., H. Mila, A. Grellet, A.Feugier, C. Mariani, J.-L. Pingret, C. Boucraut-Baralon, S. Chastant-Maillard. 2016. Excretion of canine parvovirus type 2 (CPV-2) during gestation and lactation in bitches and puppies
    >>Download this poster
    - Grellet, A., R.M. Heilmann, B. Polack, A. Feugier, C. Boucraut-Baralon, D. Grandjean, N.Grüntzner, J.S. Suchodolski, J.M. Steiner, and S. Chastant-Maillard. 2016. Influence of Breed Size, Age, Fecal Quality, and Enteropathogen Shedding on Fecal Calprotectin and Immunoglobulin A Concentrations in Puppies During the Weaning Period. Journal of Veterinary Internal Medicine 2016.
    >> Download this paper
    - Grellet, A., S. Chastant-Maillard, A. Feugier, C. Boucraut-Baralon, D. Grandjean, B. Polack. Risk factors of weaning diarrhea in puppies housed in breeding kennels. Prev Veterinary Medecine 117(1) : 260-5 Télécharger cet article
    Hepatozoon canis
    - Criado-Fornelio, A., A. Buling , N.A. Cunha-Filho, J.L. Ruas, N.A.R. Farias, C. Rey-Valeiron, J.L. Pingret, M. Etievant, J.C. Barba-Carretero. 2007. Development and evaluation of a quantitative PCR assay for detection of Hepatozoon sp.. Veterinary Parasitology 150 352–356
    Hemoprotozoa
    - Criado-Fornelio, A., A. Buling, J-L. Pingret, M. Etievant, C. Boucraut-Baralon, A. Alongi, A. Agnone, A. Torina. 2009. Hemoprotozoa of domestic animals in France: Prevalence and molecular characterization. Veterinary Parasitology 159 73–76
    Diagnostics
    - Boucraut-Baralon, C. . 2001. La PCR, un nouvel outil pour le diagnostic des maladies infectieuses chez le chien. Prat Méd Chir Anim Comp 36 : 515-521
    		 Feline retroviruses
    - Boucraut-Baralon, C. . 2000. Diagnostic de laboratoire des rétroviroses félines. Le Nouveau Praticien Vétérinaire Juin-Juillet 2000 : 45-47
    - Boucraut-Baralon, C. . 2006. La vaccination d’un chat infecté par le FIV. Le point vétérinaire, 271 12-13
    Ocular diseases
    - De Geyer, G., C. Boucraut-Baralon. 2001. Herpesvirus félin-1 et maladies oculaires chez le chat. Prat Méd Chir Anim Comp 36 : 461-471
    URI
    - Boucraut-Baralon, C. . 2002. Coryza contagieux félin. Encycl Méd Chir (Editions Scientifiques et Médicales Elsevier SAS, Paris, tous droits réservés), Encyclopédie vétérinaire (Elsevier, Paris), Médecine générale, 1800, 2002, 7p.
    Calicivirosis
    - Reynolds, B., C. Boucraut-Baralon. 2006. Diagnostic, traitement et prévention des caliciviroses félines. Le Nouveau Praticien Vétérinaire canine, féline Hors-série 2006 : 61-63
    - Reynolds, B. H. Poulet, J.-L. Pingret, D. Jas, S.Brunet, C. Lemeter, M.Etievant, C. Boucraut-Baralon. 2009. A nosocomial outbreak of feline calicivirus associated virulent systemic disease in France. Journal Of Feline Medicine and Surgery 11 : 633-644
    Feline herpesvirosis
    - Donzel, E., C. Boucraut-Baralon, S. Mazzucchelli, N. Otero Coves, T. Verite, F. Laguna, J. Piteux, C. Molas, G. Storms, G. Payen, S. Chahory. 2012. Effect of fluorescein and topical anaesthetics on pcr used for the diagnosis of feline herpesvirus related conjunctivitis.
    Feline parvovirosis (Typhus / Panleucopénie)
    - Barrault, M-J., D. Rivière, S. Guionie. 2011. Deux cas d’épanchement pleural associés à une infection par le parvovirus félin. Le Point Vétérinaire 319 : 54-58
    Mycobacteria
    - Rivière, D., J.-L. Pingret, M. Etievant, A. Jechoux, D. Lanore, I. Raymond-Letron, C. Corine Boucraut-Baralon. 2011. Disseminated Mycobacterium avium subspecies infection in a cat. Journal Of Feline Medicine and Surgery 13 : 125-128
    		 Goose Haemorrhagic Polyomavirosis
    - Guerin, J.-L., J. Gelfi, L. Dubois, A. Vuillaume, C. Boucraut-Baralon and J.-L. Pingret. May-2000. A novel polyomavirus (goose hemorrhagic polyomavirus) is the agent of hemorrhagic nephritis enteritis of geese. J Virol 74 : 4523-9.
    >>download this paper
    - Lacroux, C., O. Andreoletti, B. Payre, J.-L. Pingret, A. Dissais and J.-L. Guerin. Jun-2004. Pathology of spontaneous and experimental infections by Goose haemorrhagic polyomavirus. Avian Pathol 33: 351-8.
    - Pingret, J.-L., C. Boucraut-Baralon and J-L. Guérin. 2008. Goose haemorrhagic polyomavirus infection in ducks. Vet Record 2008 162:164.
    Derzsy et Parvovirus Canard Barbarie
    - Pingret, J.-L., C. Zadjian, S. Lemière et C. Boucraut-Baralon. 2005. Détection des Parvovirus des palmipèdes par PCR en temps réel. Journées de la Recherche Avicole 6: 423-7.
    >> Download poster and this paper
    - Fontaine, J., C. Facon, M. Castets, X. Banse, O. Albaric, J.-L. Pingret, J.-Y. Douet and J.-L. Guérin. 2009. Necrotizing splenitis in mule ducklings: case report and etiological investigations. XVIth World Veterinary Poultry Association Congress Marrakesh.
    		 Chlamydiosis (Psittacosis), PBFD and Avian Polyomavirosis (French Moult)
    - Lafon, S., J.-L. Pingret et C. Boucraut-Baralon. 2005. Real-Time PCR for diagnosis of three common infectious diseases in caged birds: Chlamydophilosis, Beak and Feather Disease and Avian Polyomavirosis. 8th European AAV Conference.
    Mycobacteria
    - Huynh, M., J.-L. Pingret, A. Nicolier. 2014. Disseminated Mycobacterium genavense Infection in a chinchilla. J Comp Pathol 151(1) : 122-5
    		 Rodent parvoviruses
    - Lafon, S., J.-L. Pingret, N. Fiks, C. Médaille et C. Boucraut-Baralon. 2004.Real-Time PCR diagnostic test of rat Parvovirus infections and genetic strain identification - Comparative study with serological patterns. 9th FELASA symposium
    >> Download this poster
    Transgenic animals
    - Lafon, S., J.-L. Pingret, M. Le Roux, V. Turquois, P.J. Ripoll, C. Boucraut-Baralon.2007. Accurate method for determination of transgene copy number using Real-time PCR in rabbits. 10th FELASA symposium
    >> Contact us to get this poster.
    		 Diagnostics
    - Boucraut-Baralon, C. . 2009. Nouvelle méthode d’investigation, la PCR en dermatologie. Le Nouveau Praticien Vétérinaire canine, féline Juin 2009 : 38-40
    - Boucraut-Baralon, C. . 2009. La PCR : Choix et réalisation des prélèvements, interprétation des résultats. PratiqueVet 44 : 42-45
    - Boucraut-Baralon, C. . 2008. La PCR : Intérêt, limites et principales indications. PratiqueVet 43 : 670-673
    - Boucraut-Baralon, C. . 2006. L’apport des techniques de biologie dans le diagnostic des maladies infectieuses. Le Nouveau Praticien Vétérinaire canine, féline Hors-série 2006 : 83-87
    - Boucraut-Baralon, C. . 2002. La PCR ou amplification génique. Prat Méd Chir Anim Comp 37 : 303-304
    - Boucraut-Baralon, C. . 2001. Diagnostic moléculaire - Les techniques PCR et la recherche d’agents pathogènes. Le Nouveau Praticien Vétérinaire Novembre-Décembre-Janvier 2001: 63-66
    - Boucraut-Baralon, C. . 2001. La PCR, un nouvel outil pour le diagnostic des maladies infectieuses chez le chien. Prat Méd Chir Anim Comp 36 : 515-521
    - Boucraut-Baralon, C. . 2001. Diagnostic - Le western blot ou "immunoblotting". Février-Mai 2001: 70-72
    - Trumel, C., C. Boucraut-Baralon. 2001. Analyse et commentaires - Interprétation de la cytologie du lavage bronchoalvéolaire. Le Nouveau Praticien Vétérinaire Novembre-Décembre-Janvier 2001 : 51-52

    Scientific partnerships

    		 Oncology
    - Lanore, D., D. Rivière, C. Delprat. 2010. Suspicion de piroplasmose chez un bouvier bernois : un diagnostic de sarcome hystiocytaire. L’essentiel 167 24-28.
    - Lanore, D., D.Rivière. 2010. Bilan d’extension du mastocytome cutané canin ; la chimiothérapie est indiquée lors de stade 2. La semaine vétérinaire 1396 32-33.
    Leishmaniasis
    - Collignon, C., A. Zahra, L. Guenego, R. Gautier, A. Madelenat. 2009. Pratique médicale et chirurgicale de l’animal de compagnie 44 27-34
    Enteritic pathogens
    - Solano-Gallego, L., L. Kidd, M. Trotta, M. Di Marco, M. Caldin, T. Furlanello, E. Breitschwerdt. 2006. Emerging Infectious Diseases Vol 12 (12) : 1985
    		 Hemobartonella
    - Beaufils, J-P.. 2012. Anémie hémolytique chez un chien infecté par Mycoplasma haemocanis. Pratique médicale et chirurgicale de l’animal de compagnie 47 43-47

  • They trust us

    • More than 2500 veterinary practices in France
    • veterinary practices in 9 other European countries
    • 18 veterinary schools in Europe
    • 6 of the 10 first international groups in animal health, including the top three ones
    • 2 of the top three pet-food worldwide groups

  • Our team

    A team of specialists in PCR & Infectious Diseases
    Corine Boucraut-Baralon CEO, Scientific manager
    		 DVM, PhD Member of ABCD (European Advisory Board for Cat Diseases, www.abcd-vets.org)

    Corine is your contact for diagnostics of infectious and parasitic diseases in cat and dog. Corine will be pleased to share her experience in risk management in catteries and kennels, from screening to treatment and vaccination.

    Competences: Virology, Infectious diseases, Vaccinology, Diagnostics of infectious diseases in animals, Medical genetics
    Agnès Poujade Consultant
    		 DVM, Pathological Anatomy Specialist (DESAPV). Member of the AFVAC-MPL board. Agnès has 25 years of experience in veterinary diagnostics.

    Agnès is your contact for infectious diseases diagnostics in domestic carnivora (dogs / cats)
    Jean-Luc Pingret R&D Director, Quality Assurance
    		 Engineer (INSA) & PhD in Molecular Biology and Biotechnology
    Jean-Luc is in charge of design, development and validation of molecular assays and PCR analyses management and monitoring.
    Responsible for Quality Assurance at Scanelis lab, Jean-Luc was a member has worked in the AFNOR (French National Association for Standardization) work group "PCR in Animal Health".

    Jean-Luc is your contact for Infectious Diseases Diagnostics in Cattle, Sheep, Goats, Poultry and Rabbits.

    Competences: Microbiology, Molecular Biology, Veterinary Molecular Diagnostics
    Sophie Lafon Business development
    		 Engineer in Molecular Biology / Biotechnology. Sophie is responsible for Marketing/Communication and LIMS
    * Laboratory Information Management System, for total automated traceability from receipt of the samples to analysis report and invoice)

    Sophie is your contact for Infectious Diseases Diagnostics in Exotics, for Health Monitoring in Lab Animals and Aquaculture and for your diagnostic special requests as a practitioner or an industrialist.

    Competences: PCR Diagnostics / PCR Diagnosis in Animal Health, Marketing & Commmunication

    Technical Team

    Suzanne Muyard Production manager, Technician, Analyses
    		 With a MS degree in Biology, Suzanne coordinates the technical team and is responsible for the analytical platform
    Suzanne is involved in the entire analytical process, from receipt of the sample to analytical validation of results
    Julie Alvarez
    Camille Bouniot
    Léa Mayeux
    Technician, Analyses
    Julie, Camille and Léa perform each step of the analytical process, in respect of a strict forward workflow of the samples: receipt of the samples, registration of the analyses/samples in our LIMS, nucleic acids purification by a specific protocol adapted to each type of biological sample, reagent preparation, liquid-handling robot operation for PCR preparation, technical validation of results for further interpretation/validation by our vets/biologists, stock management
    Mélanie Etievant R&D technician
    		 Mélanie has a BS (License) in Biotechnology and is in charge of assays in the Scanelis R&D department: development and validation of new molecular assays, evolution of the existing Scanelis quantitative PCR assays, special molecular analyses, studies and scientific collaborations

    Administrative Team

    Marlène Turpin
    Administrative assistants
    Marlene, Veterinary Assistant, Emilie and Florence, Administrative Assistants, welcome you on the phone and are in charge of administrative tasks from result report to invoice.

    Marlène and Jessie will listen to your questions about expedition of samples to Scanelis lab, edition of an analysis report or an invoice.
Site Map | Contact | RSS 2.0 | FAQ | Glossary | Legal information | Privacy Policy

Quantitative PCR testing: trust a specialist!

9 Allée Charles Cros - CS 70006 31771 Colomiers Cedex Phone+33 (0)5 34 50 50 90